*   Patents

  1. Manish Biyani & Koichi Nishigaki. “Miniaturized Micro-Gel Electrophoresis”. Japanese National Invention Patent, 11-352680, issued April 2000.
  2. Manish Biyani & Naoto Nemoto. “Linker for constructing mRNA-Puromycin-Protein conjugate”. Japanese National Invention Patent (Patent filed Nov 2, 2004; Ref No 2004-301687) and PCT International Patent (American and European Patent office; Patent filed Oct 12, 2005; Ref No JP2005-019163).
  3. Manish Biyani & Naoto Nemoto. “Solid-phase cell-free Protein synthesis for folding quality control”. Japanese National Invention Patent (Patent filed Nov 12, 2004; Ref No 2004-329493) and PCT International Patent (American Patent office; Ref No JP2005-021175).
  4. Manish Biyani & Naoto Nemoto. “High-throughput screening by solid-phase cDNA-display technology”. Japanese National Invention Patent (Patent filed Oct 18, 2005; Ref No 2005-303009) and PCT International Patent (Ref. No. JP2006-320998).
  5. Manish Biyani, Naoto Nemoto & Takanori Ichiki. “Single clone-type DNA-to-Protein chip for high throughput functional proteomics”. Japanese National Invention Patent (Patent filed Nov 1, 2006; Ref No. 2006-297267).

* Journals (Refereed papers in International Journals)

  1. Manish Biyani and Koichi Nishigaki (2001) Hundred-fold Productivity of Genome Analysis by Introduction of Micro-Temperature Gradient Gel Electrophoresis. Electrophoresis 22(1), 23-28. (abstract)
  2. Manish Biyani, Hiroshi Nishizawa, Yoshihide Miyatani, Eiichi Kanaumi, Pharhad Eli, Yasunori Kinoshita, and Koichi Nishigaki (2001) Micronized Gel Electrophoresis: Construction and Its Versatile Applications. Chemistry letters, 2, 138-139. (abstract)
  3. Manish Biyani and Koichi Nishigaki (2003) Sequence-specific and non-specific mobilities of single-stranded oligonucleotides observed by changing the borate buffer concentration. Electrophoresis, 24(4), 628-633. (abstract)
  4. Manish Biyani and Koichi Nishigaki (2005) Single-strand conformation polymorphism at the oligodeoxyribonucleotide level: An insight into solution structural dynamics of DNAs by gel electrophoresis and molecular dynamics simulations. J Biochem 138(4), 363-373. (abstract) (complete article PDF)
  5. Manish Biyani and Koichi Nishigaki (2005) Structural characterization of ultra-stable higher-ordered aggregates generated by novel guanine-rich DNA sequences. Gene364, 130-138. (abstract) (complete article PDF)
  6. Manish Biyani, Naoto Nemoto and Yuzuru Husimi (2006) Solid-phase translation and RNA-protein fusion: a novel approach for folding quality control and direct immobilization of protein using anchored mRNA. Nucleic Acids Research 34, e140. (abstract) (complete article PDF)

    forthcomings....

  1. Manish Biyani, Yoshihiro Kikkawa, Marina Murakami, Nobuhiro Saitoh, Masahiro Fujita and Koichi Nishigaki (2007) DNA directed multi-dimensional self-assembly growth for nanoarchitectures: model and evidences. (Nature Materials, to be submitted)
  2. Junichi Yamaguchi, Manish Biyani, Toru Sasaki, Yuzuru Husimi, Takashi Funatsu and Naoto Nemoto (2007) cDNA display: A novel method for rapid stabilization of mRNA-protein fusion and its application to the screening of functional proteins (Nucleic Acids Research, to be submitted).
  3. Manish Biyani and Naoto Nemoto (2008) Optimization of linker-DNA: a key molecule to drive the synthesis of RNA-protein fusion. (Biochem Biophy Res Comm, in preparation)
  4. Manish Biyani, Madhu Biyani and Naoto Nemoto (2008) Directed molecular evolution of new regulatory sequences for efficient RNA-protein fusion. (Nucleic Acids Research, in preparation)
  5. Manish Biyani, Marina Murakami and Koichi Nishigaki (2008). Effect of divalent cations and polyamines on self-assembling nature of parallel quadruplex-DNA: A minor amount of Manganese and Spermine, a drastic change in CD spectra (Nucleic Acids Research, in preparation)
  6. Manish Biyani, Keiichi Hamano, Yasushi Hirano, Motofumi Suzuki and Koichi Nishigaki (2008). State-of-the-art Genome Profiling for application in microbiology: more specific identification of Candida species. (J Microbiol Methods, in preparation)

* Books and Refereed papers in International Conferences

  1. Manish Biyani and Koichi Nishigaki. (2003) Prediction from Sequence to Structure at oligonucleotides level by MD simulations. In: Proc. of 14th International conference on Genome Informatics 2003, Gribskov, M., Kanehisa, M., Miyano, S., Takagi, T. (ed.), Universal academy press, Japan, vol.14, p.p.490-491. (Weblink)
  2. Yosuke Hosoi, Manish Biyani, Naoto Nemoto and Takanori Ichiki (2005) High-Throughput Screening of mutant AKR enzymes using mRNA display and novel microreactor array chips. In: Proc. of 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. (MicroTAS2005), Boston, USA, vol.1, p.p. 323-325.
  3. Manish Biyani and Naoto Nemoto (2005) An artificial co-evolutionary relationship between ribsome/mRNA interaction (translational initiation) and protein synthesis driven by in-vitro-virus. In: Proc. of Hayashibara Forum 2005, Okayama, Japan, vol.??, p.p??.
  4. Yosuke Hosoi, K. Takahashi, Manish Biyani, Naoto Nemoto, Takanori Akagi and Takanori Ichiki (2005) High-throughput screening of mutant biomolecules using mRNA display and microreactor array chips. In: Proc. of International Conference on Solid State Device and Materials (SSDM 2005), Kobe, Japan, pp.452-453.
  5. Manish Biyani, Keiichi Hamano, Yasushi Hirano, Motofumi Suzuki and Koichi Nishigaki (2006) Genome Profiling (GP): a universal method for inter- and intra-species identification. In: Proc. of 93rd Indian Science Congress, Mukherjee S.P. (ed.), Hyderabad, India, vol., p.p. 81.
  6. Manish Biyani, Naoto Nemoto, Yosuke Hosoi and Takanori Ichiki (2006) RNA-to-Protein Chip: an integrated microarray platform to bridge genomics and proteomics. In: Proc. of 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences. (MicroTAS2006), Tokyo, Japan, vol.1, p.p.209-211.
  7. Manish Biyani (2006) State-of-the-art Genome Profiling (GP): a key tool for plant biotechnology. In: Recent advancement in Plant Biotechnology.

* Press reports

      • CREATE (JST), 2005 (web link)
      • Rajasthan Patrika (Local Newspaper), Date (Download)